Meganisi (Greek: Μεγανήσι) is a Greek island to the east-southeast of the island of Lefkada.
The island has three villages: the central village of Katomeri (pop. 492) and the ports of Vathy (145) and Spartochori (453 inhabitants). There is also a harbour at Atheni Bay used mainly by fishing boats.
Meganisi is connected with Lefkada by a car ferry service from Vathy and Spartochori.
Meganisi has a school, a lyceum (middle school), an ATM, churches and a few squares (plateies). The island has no secondary school, so pupils attend the nearby school in Nydri, on Lefkada.