The Catholic church of Panaghia Episkopiani (our Lady of the Diocese) or Protòthroni is built in the outskirts of the village, on the way to Mallia. The epithet Episkopiani, means belonging to the bishopric thus revealing a direct relation to the Catholic diocese of Syros. Indeed, since the 16th century, if not earlier, the area was known to be the countryseat of the Bishop.
According to tradition, this church was the first Metropolitan see of Syros. The exact date of construction is not known. Some researchers say that it probably belongs between the 10th and the 11th century AD. Originally, it was an orthodox church, dedicated to Panaghia Protòthroni. It was reconstructed in 1652 with many of its early Byzantine features being kept intact. This architectural mix of styles is quite unique, because the Byzantine style was almost completely disused since the establishment of Catholicism in the islands. It is a cross-shaped sturdy construction with thick walls, topped with a dome. In 1728, the island had escaped the danger of a plague epidemic, something which was considered a miracle attributed to Virgin Mary.
Its floor is composed of five commemorative plaques made of grey and white marble, with engravings and inscriptions on them. These plaques belong to the Bottaro family (an Italian family of famous physicians) which owned a country house near the church. The inscriptions date since the 19th century and they are written in Italian.